Loading Dose of Fomepizole is Safe in Children with Presumed Toxic Alcohol Exposure - A Case Series

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Methanol is responsible for a life-threatening poisoning. Fomepizole, a potent alcohol dehydrogenase inhibitor, is an efficient and safe antidote that prevents or reduces toxic methanol metabolism. Although no study has compared its efficacy with ethanol, fomepizole is recommended as a first-line antidote. Treatment should be started as soon as possible, based on history and initial findings in...

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ژورنال

عنوان ژورنال: Basic & Clinical Pharmacology & Toxicology

سال: 2014

ISSN: 1742-7835

DOI: 10.1111/bcpt.12276